Open AccessAssociations between maternal circulating 25‐hydroxyvitamin D concentration and birth outcomes—Mode of delivery and episiotomy rate: A prospective cohort study
Author(s) -
GómezCarrascosa Inmaculada,
SánchezFerrer María L.,
ArenseGonzalo Julian J.,
PrietoSánchez María T.,
AlfoseaMarhuenda Emilia,
Iniesta Miguel A.,
Mendiola Jaime,
TorresCantero Alberto M.
Publication year - 2021
Publication title -
nursing open
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.55
H-Index - 12
ISSN - 2054-1058
DOI - 10.1002/nop2.915
Subject(s) - medicine , episiotomy , caesarean section , vaginal delivery , obstetrics , prospective cohort study , cohort study , pregnancy , observational study , statistical significance , childbirth , genetics , biology
Aim The objective of this study was to evaluate associations between maternal concentrations of 25‐hydroxyvitamin D (25(OHD)) and birth outcomes: mode of delivery and episiotomy rate. Design and Methods One hundred and seventeen pregnant women were enrolled in an observational, longitudinal, prospective cohort study. Multivariable linear regression analyses were performed to assess relationships between maternal 25(OHD) concentrations and mode of delivery. To account for systematic temporal variation in 25(OHD), a cosinor model to the data was fitted. Results No significant statistical associations were found between adjusted maternal 25(OHD) concentrations and risk of eutocic vaginal delivery, instrumented delivery (OR 1.05 [95% CI: 0.97–1.13]), primary Caesarean section (OR 0.99 [95% CI: 0.88–1.11]) or Caesarean section for any other causes (OR 1.04 [95% CI: 0.95–1.14]). High 25(OHD) levels tended to show a protective effect on performance of episiotomy, without reaching statistical significance (OR 0.36 [95% CI: 0.09, 1.37]).