
Impact of adverse events on patient outcomes in a Japanese intensive care unit: a retrospective observational study
Author(s) -
Aikawa Gen,
Ouchi Akira,
Sakuramoto Hideaki,
Ono Chiemi,
Hatozaki Chie,
Okamoto Mayu,
Hoshino Tetsuya,
Shimojo Nobutake,
Inoue Yoshiaki
Publication year - 2021
Publication title -
nursing open
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.55
H-Index - 12
ISSN - 2054-1058
DOI - 10.1002/nop2.1040
Subject(s) - medicine , adverse effect , intensive care unit , retrospective cohort study , observational study , incidence (geometry) , confidence interval , emergency medicine , medical record , intensive care , intensive care medicine , physics , optics
Aim We investigated adverse events (AEs) in a Japanese intensive care unit (ICU) and evaluated the impact of cause‐specific AEs on mortality and length of stay. Design A retrospective observational study in the ICU of an academic hospital. Methods We reviewed medical records with the Global Trigger Tool. Results Of the 246 patients, 126 (51%) experienced one or more AEs with an incidence of 201 per 1000 patient‐days and 115 per 100 admissions. A total of 294 AEs were detected with 119 (42%) adverse drug events, 67 (24%) procedural complications, 63 (22%) surgical complications, 26 (9%) nosocomial infections, 5 (2%) therapeutic errors and 4 (1%) diagnostic errors. Adverse event (AE) presence was associated with length of ICU stay (β = 2.85, 95% confidence interval [CI]: 1.09–4.61). Adverse drug events, procedural complications and nosocomial infections were strongly associated with length of ICU stay (β = 2.38, 95% CI: 0.77–3.98; β = 3.75, 95% CI: 2.03–5.48; β = 6.52, 95% CI: 4.07–8.97 respectively).