Open AccessInterganglionic axonal transport of neural peptides within the nervous system of Aplysia
Author(s) -
Berry Robert W.,
Geinisman Yuri
Publication year - 1979
Publication title -
journal of neurobiology
Language(s) - English
Resource type - Journals
eISSN - 1097-4695
pISSN - 0022-3034
DOI - 10.1002/neu.480100506
Subject(s) - aplysia , biology , axoplasmic transport , nervous system , ganglion , neuroscience , axon , connective tissue , peripheral nervous system , anatomy , central nervous system , genetics
Neurons of the circumesophageal ganglia of Aplysia synthesize 1‐2000 dalton peptides and subject them to axonal transport in large quantities in the pleuro‐visceral connective and pedal nerves. Most of the protein transported in the connective nerves accumulates in the abdominal ganglion, although some passes out its peripheral nerves. Autoradiography revealed no evidence for terminations of the transporting axons in possible neurohemal areas of this ganglion. It is suggested that these data reflect the existence of a pathway mediating the “directed delivery” of neural peptides in this nervous system.