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Hepatic Encephalopathy and Nutrition Influences: A Narrative Review
Author(s) -
Fallahzadeh Mohammad Amin,
Rahimi Robert S.
Publication year - 2020
Publication title -
nutrition in clinical practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.725
H-Index - 71
eISSN - 1941-2452
pISSN - 0884-5336
DOI - 10.1002/ncp.10458
Subject(s) - medicine , cirrhosis , hepatic encephalopathy , neurocognitive , intensive care medicine , encephalopathy , disease , epidemiology , narrative review , liver disease , pathophysiology , pediatrics , psychiatry , cognition
Hepatic encephalopathy (HE) is a potentially reversible neurocognitive condition seen in patients with advanced liver disease. The overt form of HE has been reported in up to 45% of patients with cirrhosis. This debilitating condition is associated with increased morbidity and mortality and imposes a significant burden on the caregivers and healthcare system. After providing an overview of HE epidemiology and pathophysiology, this review focuses on the interaction of HE and frailty, nutrition requirements and recommendations in cirrhotic patients with HE, and current dietary and pharmacologic options for HE treatment.