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Magnetization transfer in MRI: a review
Author(s) -
Henkelman R. M.,
Stanisz G. J.,
Graham S. J.
Publication year - 2001
Publication title -
nmr in biomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 114
eISSN - 1099-1492
pISSN - 0952-3480
DOI - 10.1002/nbm.683
Subject(s) - magnetization transfer , nuclear magnetic resonance , magnetization , magnetic resonance imaging , interpretation (philosophy) , contrast (vision) , physics , saturation (graph theory) , computer science , statistical physics , materials science , biological system , artificial intelligence , medicine , radiology , magnetic field , mathematics , biology , programming language , quantum mechanics , combinatorics
This review describes magnetization transfer (MT) contrast in magnetic resonance imaging. A qualitative description of how MT works is provided along with experimental evidence that leads to a quantitative model for MT in tissues. The implementation of MT saturation in imaging sequences and the interpretation of the MT‐induced signal change in terms of exchange processes and direct effects are presented. Finally, highlights of clinical uses of MT are outlined and future directions for investigation proposed. Copyright © 2001 John Wiley & Sons, Ltd.Abbreviations used: B eff effective magnetic fieldCRMG Carr–Purcell–Meiboom–GillCW continuous waveFAIR flow sensitive alternating inversion recoveryGd‐DTPA gadolinium diethylenetriminepentaacetic acidMRA magnetic resonance angiographyMRI magnetic resonance imagingMS multiple sclerosisMT magnetization transferMTR magnetization transfer ratioRF radio frequencySAR specific absorption rate.