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Clinical evaluation of time‐of‐flight MR angiography with sparse undersampling and iterative reconstruction for cerebral aneurysms
Author(s) -
Fushimi Yasutaka,
Okada Tomohisa,
Kikuchi Takayuki,
Yamamoto Akira,
Okada Tsutomu,
Yamamoto Takayuki,
Schmidt Michaela,
Yoshida Kazumichi,
Miyamoto Susumu,
Togashi Kaori
Publication year - 2017
Publication title -
nmr in biomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 114
eISSN - 1099-1492
pISSN - 0952-3480
DOI - 10.1002/nbm.3774
Subject(s) - undersampling , cerebral angiography , radiology , medicine , angiography , computer science , magnetic resonance angiography , artificial intelligence , magnetic resonance imaging
Compressed sensing (CS) MRI has just been introduced to research areas as an innovative approach to accelerate MRI. CS is expected to achieve higher k ‐space undersampling by exploiting the underlying sparsity in an appropriate transform domain. MR angiography (MRA) provides high spatial resolution information on arteries; however, a relatively long acquisition time is necessary to cover a wide volume. Reduction of acquisition time by CS for time‐of‐flight (TOF) MR angiography (Sparse‐TOF) is beneficial in clinical examinations; therefore, the clinical validity of Sparse‐TOF needs to be investigated. The aim of this study was to compare the diagnostic capability of TOF MRA between parallel imaging (PI)‐TOF with an acceleration factor of 3 (annotated as 3×) and Sparse‐TOF (3× and 5×) in patients with cerebral aneurysms. PI‐TOF (3×) and Sparse‐TOF (3× and 5×) imaging were performed in 20 patients using a 3 T MRI system. Aneurysms in PI‐TOF (3×) and Sparse‐TOF (3× and 5×) were blindly rated as visible or scarcely visible by neuroradiologists. The neck, height and width of aneurysms were also measured. Twenty‐six aneurysms were visualized and rated as visible in PI‐TOF (3×) and Sparse‐TOF (3× and 5×), with excellent agreement between two raters. No significant differences were found in measured neck, height or width of aneurysms among them. Sparse‐TOF (3× and 5×) were acquired and reconstructed within 6 min, and cerebral aneurysms were visible in both of them with equivalent quality to PI‐TOF (3×). Sparse‐TOF (5×) is a good alternative to PI‐TOF (3×) to visualize cerebral aneurysms.

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