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Intraventricular temperature measured by diffusion‐weighted imaging compared with brain parenchymal temperature measured by MRS in vivo
Author(s) -
Sumida Kaoru,
Sato Noriko,
Ota Miho,
Sakai Koji,
Sone Daichi,
Yokoyama Kota,
Kimura Yukio,
Maikusa Norihide,
Imabayashi Etsuko,
Matsuda Hiroshi,
Kunimatsu Akira,
Ohtomo Kuni
Publication year - 2016
Publication title -
nmr in biomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 114
eISSN - 1099-1492
pISSN - 0952-3480
DOI - 10.1002/nbm.3542
Subject(s) - parenchyma , diffusion mri , nuclear medicine , medicine , negative correlation , correlation , magnetic resonance imaging , nuclear magnetic resonance , pathology , radiology , mathematics , physics , geometry
We examined and compared the temperatures of the intraventricular cerebrospinal fluid ( T v ) and the brain parenchyma ( T p ) using MRI, with reference to the tympanic membrane temperature ( T t ) in healthy subjects. We estimated T v and T p values from data gathered simultaneously by MR diffusion‐weighted imaging (DWI) and MRS, respectively, in 35 healthy volunteers (17 males, 18 females; age 25–78 years). We also obtained T t values just before each MR examination to evaluate the relationships among the three temperatures. There were significant positive correlations between T v and T p ( R = 0.611, p < 0.001). The correlation was also significant after correction for T t ( R = 0.642, p < 0.001). There was no significant correlation between T v and T t or between T p and T t in the men or the women. Negative correlations were found between T v and age and between T p and age in the males but not females. DWI thermometry seems to reflect the intracranial environment as accurately as MRS thermometry. An age‐dependent decline in temperature was evident in our male subjects by both DWI and MRS thermometry, probably due to the decrease in cerebral metabolism with age. Copyright © 2016 John Wiley & Sons, Ltd.