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Sodium NMR/MRI for anisotropic systems
Author(s) -
Eliav U.,
Navon G.
Publication year - 2016
Publication title -
nmr in biomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 114
eISSN - 1099-1492
pISSN - 0952-3480
DOI - 10.1002/nbm.3331
Subject(s) - anisotropy , nuclear magnetic resonance , rotational diffusion , nuclear magnetic resonance spectroscopy , sodium , chemistry , ion , magnetization transfer , biophysics , magnetic resonance imaging , physics , biology , optics , organic chemistry , medicine , radiology
Sodium ( 23 Na) plays a central role in many physiological processes, and its high NMR sensitivity makes it an attractive nucleus for biomedical NMR and MRI research. Many biological tissues contain structures such as fibers and membranes that impose anisotropic translational and rotational motions on the sodium ions. Translational motion can be studied by diffusion measurements. Anisotropic rotational motion results in non‐vanishing quadrupolar interaction that it is best studied by exploiting multiple quantum coherences for 23 Na NMR spectroscopy and MRI. The current review covers the application of the various NMR techniques to the study of 23 Na in anisotropic compartments in cartilage, tendon, intervertebral discs, red blood cells, nervous system and muscles. Copyright © 2015 John Wiley & Sons, Ltd.