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Diffusion‐weighted MRI and its role in prostate cancer
Author(s) -
Tamada Tsutomu,
Sone Teruki,
Jo Yoshimasa,
Yamamoto Akira,
Ito Katsuyoshi
Publication year - 2014
Publication title -
nmr in biomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 114
eISSN - 1099-1492
pISSN - 0952-3480
DOI - 10.1002/nbm.2956
Subject(s) - diffusion mri , prostate cancer , effective diffusion coefficient , magnetic resonance imaging , multiparametric mri , prostate , medicine , dynamic contrast enhanced mri , radiology , dynamic contrast , nuclear medicine , contrast (vision) , cancer , computer science , artificial intelligence
In the last 5 years, the multiparametric approach has been investigated as the method for the MRI of prostate cancer. In multiparametric MRI of the prostate, at least two functional MRI techniques, such as diffusion‐weighted MRI (DW‐MRI) and dynamic contrast‐enhanced MRI, are combined with conventional MRI, such as T 2 ‐weighted imaging. DW‐MRI has the ability to qualitatively and quantitatively represent the diffusion of water molecules by the apparent diffusion coefficient, which indirectly reflects tissue cellularity. DW‐MRI is characterized by a short acquisition time without the administration of contrast medium. Thus, DW‐MRI has the potential to become established as a noninvasive diagnostic method for tumor detection and localization, tumor aggressiveness, local staging and local recurrence after various therapies. Accordingly, radiologists should recognize the principles of DW‐MRI, the methods of image acquisition and the pitfalls of image interpretation. Copyright © 2013 John Wiley & Sons, Ltd.