A fast method for  in vivo  lactate imaging | Zendy

Reese T. | Zendy; Norris D. G. | Zendy; Leibfritz D. | Zendy

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A fast method for in vivo lactate imaging

Author(s) -

Reese T.,

Norris D. G.,

Leibfritz D.

Publication year - 1995

Publication title -

nmr in biomedicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.278

H-Index - 114

eISSN - 1099-1492

pISSN - 0952-3480

DOI - 10.1002/nbm.1940080507

Subject(s) - gerbil , in vivo , imaging phantom , biomedical engineering , image quality , chemistry , materials science , nuclear medicine , computer science , ischemia , medicine , biology , artificial intelligence , microbiology and biotechnology , image (mathematics)

A robust method for fast lactate imaging is presented using a combination of a lactate editing sequence and a one‐shot imaging experiment. The lactate editing method is based on manipulation of the phase of the lactate CH 3 signal via J ‐modulation. This is applied as a preparation experiment to the U‐FLARE imaging sequence. Phantom experiments are presented in which the quality of water and lipid suppression is established. Edited lactate images with a spatial resolution of 3 m̈L and total measuring time of 15.8 min are shown. These were obtained from a hemispherical ischemia in the gerbil brain. The images are compared with diffusion‐weighted water images.

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