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Practical applications of chemical shift imaging
Author(s) -
Brown Truman R.
Publication year - 1992
Publication title -
nmr in biomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 114
eISSN - 1099-1492
pISSN - 0952-3480
DOI - 10.1002/nbm.1940050508
Subject(s) - signal (programming language) , artifact (error) , encoding (memory) , computer science , phase (matter) , function (biology) , point (geometry) , radio frequency , nuclear magnetic resonance , physics , biological system , algorithm , mathematics , artificial intelligence , telecommunications , biology , genetics , geometry , quantum mechanics , programming language
Methods of spectral localization are briefly reviewed and divided into two classes: those using phase encoding and those using frequency selective RF pulses in a constant gradient. A potentially troubling artifact in the latter case is the spatial misregistration of different compounds which causes serious errors in 31 P spectra from smaller regions. Chemical shift imaging (CSI) is presented as a typical example of phase encoding techniques. An analytical expression for the relationship of the signal observed to the true signal (the point spread function) is derived. Examples of CSI in one, two, and three dimensions are used to illustrate the principles of this type of localization.