Premium
The biochemistry of living tissues: Examination by MRS
Author(s) -
Ross Brian D.
Publication year - 1992
Publication title -
nmr in biomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 114
eISSN - 1099-1492
pISSN - 0952-3480
DOI - 10.1002/nbm.1940050504
Subject(s) - intermediary metabolism , creatine , metabolism , biochemistry , chemistry , physiology , biology
MRS defines the molecular state of water, the chemical environment of cells and tissues and the qualitative and quantitative state of intermediary metabolism. Because cancer has disordered physiology, obvious differences in MR spectra can be observed. However, the detailed understanding of the biochemistry of cancer will also emerge from careful, quantitative multinuclear MR. The intermediary metabolism of ATP, the Krebs cycle, creatine, cholines and lipids, is discussed. Finally, the biochemical challenge posed by oncogenes may be amenable to MR analyses.