Premium
NMR methods for measuring membrane transport rates
Author(s) -
Kirk Kiaran
Publication year - 1990
Publication title -
nmr in biomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 114
eISSN - 1099-1492
pISSN - 0952-3480
DOI - 10.1002/nbm.1940030102
Subject(s) - membrane , transmembrane protein , membrane transport , relaxation (psychology) , chemistry , membrane transport protein , nuclear magnetic resonance , biophysics , chemical physics , membrane protein , physics , biology , biochemistry , receptor , neuroscience
NMR methods for measuring membrane transport rates rely in most cases upon there being a significant transmembrane difference in either the resonance frequency or the NMR relaxation times of the transported species. The first part of this review examines the various factors that can give rise to such differences in cell and vesicle suspensions. The second part provides an introduction to the theory of membrane transport measurements and describes the different ways in which transmembrane differences in NMR parameters have been exploited in monitoring both slow and fast membrane transport processes.