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Comparison of single‐shot localization methods (steam and press) for In vivo proton NMR spectroscopy
Author(s) -
Moonen Chrit T. W.,
Kienlin Markus Von,
Van Zijl Peter C. M.,
Cohen Jack,
Gillen Joe,
Daly Peter,
Wolf Gerald
Publication year - 1989
Publication title -
nmr in biomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 114
eISSN - 1099-1492
pISSN - 0952-3480
DOI - 10.1002/nbm.1940020506
Subject(s) - proton , nuclear magnetic resonance , nuclear magnetic resonance spectroscopy , signal (programming language) , diffusion , in vivo , echo (communications protocol) , chemistry , biological system , spectroscopy , sensitivity (control systems) , proton nmr , intensity (physics) , computer science , analytical chemistry (journal) , physics , optics , nuclear physics , chromatography , thermodynamics , biology , electronic engineering , quantum mechanics , computer network , microbiology and biotechnology , engineering , programming language
Two single‐shot localization techniques, STEAM and PRESS, are analyzed with regard to specifications for in vivo localized proton NMR. In particular, attention is paid to optimum signal intensity per unit volume, sensitivity to motion and diffusion, shortest attainable echo time, water suppression and editing possibilities. Experimental results are shown for cat brain at 4.7 T and human brain at 1.5 T. Both STEAM and PRESS are highly effective localization methods. For long echo times, PRESS is the method of choice, because it offers a factor of two gain in signal intensity. In addition, the method is less sensitive to motion and diffusion, and not susceptible to multiple‐quantum effects. STEAM offers advantages for observation of (coupled) metabolites with short T 2 , because (a) shorter TEs can be attained and (b) effective water suppression sequences can be implemented without penalty in echo time. Differences relating to editing possibilities and B 1 dependence, possibly important in choosing a method, are discussed.