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Synchronous acquisition of hyperpolarised 3 He and 1 H MR images of the lungs – maximising mutual anatomical and functional information
Author(s) -
Wild Jim M.,
Ajraoui Salma,
Deppe Martin H.,
Parnell Steven R.,
Marshall Helen,
ParraRobles Juan,
Ireland Rob H.
Publication year - 2011
Publication title -
nmr in biomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 114
eISSN - 1099-1492
pISSN - 0952-3480
DOI - 10.1002/nbm.1565
Subject(s) - physics , nuclear magnetic resonance
The development of hybrid medical imaging scanners has allowed imaging with different detection modalities at the same time, providing different anatomical and functional information within the same physiological time course with the patient in the same position. Until now, the acquisition of proton MRI of lung anatomy and hyperpolarised gas MRI of lung function required separate breath‐hold examinations, meaning that the images were not spatially registered or temporally synchronised. We demonstrate the spatially registered concurrent acquisition of lung images from two different nuclei in vivo . The temporal and spatial registration of these images is demonstrated by a high degree of mutual consistency that is impossible to achieve in separate scans and breath holds. Copyright © 2010 John Wiley & Sons, Ltd.