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Effects of motion and b‐matrix correction for high resolution DTI with short‐axis PROPELLER‐EPI
Author(s) -
Aksoy Murat,
Skare Stefan,
Holdsworth Samantha,
Bammer Roland
Publication year - 2010
Publication title -
nmr in biomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 114
eISSN - 1099-1492
pISSN - 0952-3480
DOI - 10.1002/nbm.1490
Subject(s) - diffusion mri , distortion (music) , diffusion , white matter , tensor (intrinsic definition) , propeller , physics , matrix (chemical analysis) , fractional anisotropy , motion (physics) , computer science , algorithm , nuclear magnetic resonance , mathematics , chemistry , geometry , classical mechanics , geology , magnetic resonance imaging , medicine , amplifier , oceanography , optoelectronics , cmos , chromatography , radiology , thermodynamics
Short‐axis PROPELLER‐EPI (SAP‐EPI) has been proven to be very effective in providing high‐resolution diffusion‐weighted and diffusion tensor data. The self‐navigation capabilities of SAP‐EPI allow one to correct for motion, phase errors, and geometric distortion. However, in the presence of patient motion, the change in the effective diffusion‐ encoding direction (i.e. the b‐matrix) between successive PROPELLER ‘blades’ can decrease the accuracy of the estimated diffusion tensors, which might result in erroneous reconstruction of white matter tracts in the brain. In this study, we investigate the effects of alterations in the b‐matrix as a result of patient motion on the example of SAP‐EPI DTI and eliminate these effects by incorporating our novel single‐step non‐linear diffusion tensor estimation scheme into the SAP‐EPI post‐processing procedure. Our simulations and in‐vivo studies showed that, in the presence of patient motion, correcting the b‐matrix is necessary in order to get more accurate diffusion tensor and white matter pathway reconstructions. Copyright © 2010 John Wiley & Sons, Ltd.