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Single‐scan quantitative T 2 * methods with susceptibility artifact reduction
Author(s) -
Franconi Florence,
Mowat Pierre,
Lemaire Laurent,
Richomme Pascal,
Le Jeune JeanJacques
Publication year - 2006
Publication title -
nmr in biomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 114
eISSN - 1099-1492
pISSN - 0952-3480
DOI - 10.1002/nbm.1014
Subject(s) - artifact (error) , reduction (mathematics) , chemistry , computer science , artificial intelligence , mathematics , geometry
Two imaging methods, MSSAVE (Multiple echo SubSlice AVEraging imaging), based on sub‐slice averaging and MGESEPI (Multiple echo Gradient‐Echo Slice‐Excitation Profile Imaging), based on over‐sampling in the slice direction, are proposed for single‐scan quantitative T 2 * evaluation with susceptibility artifact compensation. Their potentials in terms of sensitivity, minimum performance time, susceptibility artifact reduction and T 2 * quantitation quality, were compared with existing single‐scan methods such as classical FLASH two‐ or three‐dimensional or z ‐shimmed methods both in vitro and in vivo in normal rat brain. MGESEPI offered good quality T 2 * maps nearly free of artifacts but required a long acquisition time. MSSAVE was faster, but at the expense of reduced artifact compensation and the achievable T 2 * quantitation quality. Copyright © 2006 John Wiley & Sons, Ltd.