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Pelvic floor reconstructive surgery under local anesthesia: A systematic review and meta‐analysis
Author(s) -
Zacharakis Dimitrios,
Prodromidou Anastasia,
Douligeris Athanasios,
Hadzilia Sofia,
Kathopoulis Nikolaos,
Athanasiou Stavros,
Grigoriadis Themos
Publication year - 2021
Publication title -
neurourology and urodynamics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 90
eISSN - 1520-6777
pISSN - 0733-2467
DOI - 10.1002/nau.24691
Subject(s) - medicine , sedation , confidence interval , nausea , pelvic floor , reconstructive surgery , anesthesia , anesthetic , surgery , local anesthesia , meta analysis , local anesthetic
Aims The decision on the appropriate type of anesthesia for pelvic floor repair depends on a variety of factors including patients' age, performance status, comorbidities, cost‐effectiveness and personal preferences. We aim to review the literature on urogynecological procedures performed under local anesthesia (LA). Methods A systematic search of four electronic databases was conducted for articles published up to May 2020. Studies reporting outcomes of women who underwent pelvic floor reconstructive surgery under LA with or without sedation, were considered eligible. Results Nineteen studies (14 noncomparative and 5 comparative), including 1626 cases of urogynecological procedures under LA were recruited. Meta‐analysis revealed significantly lower mean pain scores in LA group compared to general‐regional anesthesia one (GA/RA) at both 4–6 h and 8–18 h postoperatively (160 patients; mean difference [MD], −1.70; 95% confidence interval [CI]: −3.12, −0.28; p = 0.02 and 160 patients; MD, −0.72; 95% CI: −1.17, 0.27; p = 0.002, respectively). Pain scores at >24 h did not differ among the two groups (160 patients; MD, −0.28; 95% CI: −0.60–0.05; p = 0.10). Intra‐ and postoperatively morphine use was not different among patients who received LA and GA during prolapse surgery while nausea rates were significantly lower in LA group compared to RA group 8 h postoperatively. Conclusions LA with or without sedation represents a safe and efficient alternative anesthetic technique for urogynecological procedures with improved pain scores in up to 18 h postoperatively especially in patients who underwent surgery for SUI. LA is feasible and could be offered to patients undergoing pelvic floor surgery allowing a prompt postoperative recovery.