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Nonablative transurethral Erbium:YAG laser treatment for chronic prostatitis/chronic pelvic pain syndrome: A prospective comparative study
Author(s) -
Gaspar Adrián,
Silva Joaquín,
Silva Gustavo,
Anchelerguez Raúl,
Prats Jorge,
Sagaz Alejandro,
Rovere Eduardo,
Alastra Mauricio,
Pino Juan,
Jauregui Alejandro,
Farrugia Marcos,
Villaroel Fabricio,
Guareschi Jonathan,
Vega Maximiliano,
Biasiori Emanuel,
Moyano Emanuel,
La Rosa Antonio,
Hreljac Irena,
Vižintin Zdenko
Publication year - 2021
Publication title -
neurourology and urodynamics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 90
eISSN - 1520-6777
pISSN - 0733-2467
DOI - 10.1002/nau.24551
Subject(s) - medicine , tadalafil , visual analogue scale , international prostate symptom score , prostatitis , adverse effect , prospective cohort study , erectile dysfunction , pelvic pain , urology , prostate , surgery , lower urinary tract symptoms , cancer
Aims This prospective study aimed to compare the clinical outcomes between the use of Erbium:YAG (Er:YAG) laser in a nonablative mode, to the use of the pharmacological treatment of oral tadalafil for the treatment of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). Methods The laser group received two sessions of Erbium:YAG laser, administered intraurethrally in a long, nonablative train of long pulses (SMOOTH™ mode), applied at the level of the male prostatic urethra. Tadalafil group received oral tadalafil at a dose of 5 mg/day, consecutively for 2 months. Effectiveness was assessed using the International Prostate Symptom Score (IPSS) questionnaire, VAS (visual analogue scale) pain score, and maximum urethral flow at follow‐up visits up to 12 months after initiating treatment. Adverse effects were recorded after each treatment and follow‐up sessions. Results The results show a significant decrease in the IPSS score in both groups up to the 12‐month follow‐up. The increase in Q‐max was evident up to 3‐months follow‐up in the tadalafil group and up to 6 months in the laser group. The decrease in the VAS pain score was also significant in both treatment groups, lasting up to 3 months in the tadalafil group and up to 6 months in the laser group. Conclusions The nonablative Er:YAG SMOOTH™ laser seems to be a promising treatment for this widely occurring condition. More studies are needed to confirm its safety and efficacy.