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Valsalva urethral profile (VUP): A urodynamic measure to assess stress urinary incontinence in women
Author(s) -
Dompeyre Philippe,
Pizzoferrato AnneCécile,
Le Normand Loïc,
Bader Georges,
Fauconnier Arnaud
Publication year - 2020
Publication title -
neurourology and urodynamics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 90
eISSN - 1520-6777
pISSN - 0733-2467
DOI - 10.1002/nau.24386
Subject(s) - medicine , urinary incontinence , valsalva maneuver , urology , stress incontinence , population , prospective cohort study , surgery , gynecology , blood pressure , environmental health
Aims We aimed to assess the value of the Valsalva urethral profile (VUP) in case of stress urinary incontinence (SUI). Methods Six hundred and ninety‐four women without pelvic organ prolapse were included in this prospective monocentric study. SUI was diagnosed from symptoms using the International Continence Society definition, and severity using two validated questionnaires (USP and ICIQ‐SF). The urodynamic parameters studied were maximal urethral closure pressure (MUCP) and functional length (FL). Both were performed at rest, during a Valsalva maneuver (v‐MUCP and v‐FL) and again at rest. Correlation analyses and ROC curves were used to assess the value of the clinical and urodynamic measurements. Results In our population, based on the questionnaires, 172 (24.8%) women were diagnosed with pure SUI on symptoms, 71 (10.2%) with urgency urinary incontinence and 392 (56.5%) with mixed urinary incontinence; 59 (8.5%) women were continent. The v‐MUCP was the most correlated parameter to the severity of SUI ( ρ : −0.63) and the most predictive of SUI risk, with a threshold value of 35 cm H 2 O (Se = 0.82, Sp = 0.86). The v‐FL was significantly shortened in case of SUI. Conclusions The v‐MUCP and v‐FL are global measurements of urethral resistance during stress. With a threshold value of 35 cm H 2 O, the v‐MUCP was the most discriminating parameter for the diagnosis of SUI, with a good reliability.