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Evaluation of lower urinary tract symptoms in children with Down syndrome: A prospective, case‐controlled cohort study
Author(s) -
Kızılay Fuat,
İrer Bora,
Özalp Kızılay Deniz,
Şimşir Adnan,
Kalemci Serdar,
Şen Volkan,
Altay Barış,
Çoğulu Özgür
Publication year - 2020
Publication title -
neurourology and urodynamics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 90
eISSN - 1520-6777
pISSN - 0733-2467
DOI - 10.1002/nau.24293
Subject(s) - medicine , overactive bladder , urinary incontinence , dysfunctional family , lower urinary tract symptoms , prospective cohort study , cohort , urinary urgency , population , physical therapy , pediatrics , urology , clinical psychology , prostate , alternative medicine , pathology , cancer , environmental health
Aims In children with Down syndrome (DS) which causes cognitive impairment and intellectual disability (ID), dysfunctional voiding is proposed to be more common than in the normal population. In this study, we aimed to compare the voiding symptoms of DS children with a control group by validated questionnaires. Methods Thirty‐seven DS children without any previous urological complaints and 59 non‐DS healthy children as control group was included in the study. Overactive bladder symptoms and dysfunctional voiding were evaluated with validated Overactive Bladder Questionnaire (OAB‐V8) and Dysfunctional Voiding Symptom Score (DVSS) questionnaire, respectively. Data were arranged, descriptive and comparative statistical analysis were performed. Results Demographic data of the two groups were similar except age of completing toilet training being higher in DS group. Total OAB‐V8 and DVSS scores were significantly higher in the DS group. The mean scores of questions regarding voiding frequency, urgency and urgency incontinence in OAB‐V8 were significantly higher in the DS group. The mean daytime incontinence, urgency, urgency incontinence, and quality of life scores in the DVSS were also significantly higher in the DS group. Conclusions DS children have more frequent dysfunctional voiding than the normal population. ID of these children may prevent the expression of these symptoms. Awareness and early detection of these symptoms are crucial to prevent devastating complications such as renal failure. Therefore, validated questionnaires are simple, useful, and noninvasive methods.

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