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Predictors for detrusor overactivity following extensive vaginal pelvic reconstructive surgery
Author(s) -
Lo TsiaShu,
Nagashu Shailaja,
Hsieh WuChiao,
UyPatrimonio Ma Clarissa,
YiHao Lin
Publication year - 2018
Publication title -
neurourology and urodynamics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 90
eISSN - 1520-6777
pISSN - 0733-2467
DOI - 10.1002/nau.23273
Subject(s) - medicine , concomitant , surgery , overactive bladder , pelvic floor dysfunction , bladder outlet obstruction , urology , pelvic floor , prostate , alternative medicine , pathology , cancer
Aim This study aims to identify the predictors for detrusor overactivity (DO) in women following extensive vaginal pelvic reconstructive surgery (PRS) for advanced pelvic organ prolapse (POP). Methods We enrolled 1503 women who had prolapse POP‐Q stage ≥ 3 and underwent vaginal PRS with or without MUS from January 2006 to December 2015. All subjects completed a 72‐h voiding diary, IIQ‐7, UDI‐6, POPDI‐6, and PISQ‐12. Urodynamics (UDS) was performed pre‐ and post‐operatively. Results Among 1503 women, 56 patients were excluded due to incomplete data. Women who had trans‐vaginal mesh were 1083 of 1447 (74.8%) and concomitant MUS were 353 (24.4%). Pre‐operative DO were 245 (16.9%) and 24.5% (60/245) of them continued to have persistent DO post‐operatively. Women who had normal pre‐operative stable detrusor were 1202 (83.1%) and 3.5% (30/1202) developed de novo DO post‐operatively. The overall incidence of post‐operative DO was 6.2% (90/1447). Patients with age ≥66 year, neurological factors like Cerebrovascular accident and Parkinsonian disease, pre‐operative bladder outlet obstruction (BOO) maximum urethral closure pressure (MUCP) ≥60 cmH 2 O, Maximum flow rate (MFR) <15 mL/s and detrusor at maximum flow (Dmax) ≥20 cmH 2 O) and post‐void residue (PVR) ≥200 mL hold a significant higher risk of developing DO either persistent or de novo following PRS. Conclusion Age ≥66 year, neurological factors like CVA and Parkinsonian disease, pre‐operative MUCP ≥60 cmH 2 O, MFR < 15 mL, Dmax ≥ 20 cmH 2 O, and PVR ≥ 200 mL are independent risk factors for developing post‐operative DO following vaginal PRS for advanced POP.