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Impact of intravesical onabotulinumtoxinA on sexual function in women with OAB
Author(s) -
Miotla Pawel,
Cartwright Rufus,
Skorupska Katarzyna,
Bogusiewicz Michal,
MarkutMiotla Ewa,
Futyma Konrad,
Rechberger Tomasz
Publication year - 2017
Publication title -
neurourology and urodynamics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 90
eISSN - 1520-6777
pISSN - 0733-2467
DOI - 10.1002/nau.23148
Subject(s) - medicine , overactive bladder , sexual function , urology , sexual dysfunction , urinary incontinence , gynecology , alternative medicine , pathology
Aims Urgency urinary incontinence (UUI), and the symptoms of overactive bladder (OAB) have a negative impact on female sexual function. The aim of this study was to investigate the effect of intravesical onabotulinumtoxinA (Botox) injection on sexual function in women with OAB, using the multi domain Female Sexual Function Index (FSFI) questionnaire. Methods Sixty‐eight sexually active women with idiopathic OAB with at least one episode of UUI and ≥8 micturitions per 24 h were recruited. Patients completed the FSFI questionnaire before and 12 weeks after treatment with intravesical onabotulinumtoxinA injections. Baseline scores were compared with a control group of age‐matched healthy women. Results Fifty‐six women completed the study. At baseline OAB patients reported decreased quality of sexual function in all domains measured with FSFI, in comparison to healthy women (median 21.8 vs. 26.3, P < 0.001). Over 90% of participants reported clinically relevant improvements in sexual function, with statistically significant changes in mean scores in all six domains. Conclusions Intravesical Botox injections provide improvement in sexual function in women with OAB. Neurourol. Urodynam. 9999:XX–XX, 2016 . © 2016 Wiley Periodicals, Inc.