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Fiber type composition of pubococcygeus and bulbospongiosus striated muscles is modified by multiparity in the rabbit
Author(s) -
LópezGarcía Kenia,
MariscalTovar Silvia,
SerranoMeneses Martín Alejandro,
Castelán Francisco,
MartínezGómez Margarita,
JiménezEstrada Ismael
Publication year - 2017
Publication title -
neurourology and urodynamics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 90
eISSN - 1520-6777
pISSN - 0733-2467
DOI - 10.1002/nau.23143
Subject(s) - medicine , fiber , anatomy , striated muscles , rabbit (cipher) , fiber type , composite material , skeletal muscle , statistics , materials science , mathematics
Aims We analyzed the effect of multiparity on the fiber type composition of two skeletal muscles involved in the maintenance of the micturition process, the pelvic pubococcygeus (Pc) and perineal bulbospongiosus (Bs) muscles in nulliparous and multiparous rabbits ( Oryctolagus cuniculus ). Methods We used the basic ATPase and NADH‐TR techniques to identify and characterize slow, intermediate, and fast fiber types and glycolitic and oxidative fibers in muscles, respectively. Results Pc muscles of multiparous rabbits present relatively high percentages of slow and intermediate fibers but a low percentage of fast fibers ( P < 0.05) as compared to Pc muscles from nulliparous rabbits, while percentages of glycolytic and oxidative fibers were similar ( P > 0.05). Bs muscles of multiparous rabbits had a higher proportion of intermediate and glycolytic fibers ( P < 0.05) than muscles of nulliparous. Both, Pc and Bs muscles of nulliparous and multiparous rabbits contain slow fibers with similar large cross sectional area, but fast fibers in multiparous muscles showed small cross sectional area than in nulliparous. Conclusions Multiparity modified the fiber type composition of Pc and Bs muscles in female rabbits. We propose that the contractile force and the physiological role of both muscles during micturition are affected because of the observed changes in the relative composition of muscle fiber types.