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Prospective evaluation of Peristeen ® transanal irrigation system with the validated neurogenic bowel dysfunction score sheet in the pediatric population
Author(s) -
Kelly Maryellen S.,
Dorgalli Crystal,
McLorie Gordon,
Khoury Antoine E.
Publication year - 2017
Publication title -
neurourology and urodynamics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 90
eISSN - 1520-6777
pISSN - 0733-2467
DOI - 10.1002/nau.22979
Subject(s) - medicine , lumbar , population , prospective cohort study , surgery , gastroenterology , environmental health
Aims To determine the ability of Peristeen ® transanal irrigation system to reduce symptoms of neurogenic bowel dysfunction (NBD) in patients using the validated neurogenic bowel dysfunction scoring system for the pediatric population. Methods Patients 3–21 years with NBD whose current bowel program was unsuccessful were given the Neurogenic Bowel Dysfunction (NBoDS) score sheet before initiating Peristeen®, and at 2 weeks, 2 months, and 6 months after. All patients were started on Peristeen ® with tap water (20 ml/kg) per daily irrigation. Mean and paired t ‐tests were completed. Results 24 patients were enrolled and had follow‐up. Mean age was 10.5 years (range 3–21 years), 25%, 50%, 25% had thoracic, lumbar and sacral level lesions respectively. Mean NBoDS score at initiation of Peristeen® was 20.21 (±5.56), n = 24. The mean score after two weeks of use was 12.75 (±4.40), n = 24. There was a statistically significant decrease of 7.46 (95%CI, 5.07–9.84) points, t(23) = 6.47, P < 0.0005 after two weeks. There was a statistically significant decrease in their scores from initiation to the 2 month time period of 7.00 (95%CI, 2.18–11.82) points, t(9) = 3.29, P = 0.009. By the sixth month of daily use the mean NBoDS score was 9.67 (n = 12). This was an average decrease of 8.83 (95%CI, 5.39–12.28) points from initiation score, t(11) = 5.641, P < 0.005. Conclusion The Peristeen® transanal irrigation system provides a significant reduction in NBoDS scores in pediatric patients with NBD. Peristeen® should be considered when other conservative bowel management options have been unsuccessful. Neurourol. Urodynam. 36:632–635, 2017 . © 2016 Wiley Periodicals, Inc.