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Sphincter electromyography in diabetes mellitus and multiple system atrophy
Author(s) -
Jian Fan,
Pan Hua,
Zhang Zaiqiang,
Lin Jinxi,
Chen Na,
Zhang Lei,
Wu Qing,
Wang Han,
Wang Yongjun,
Cui Liying,
Tang Xiaofu
Publication year - 2015
Publication title -
neurourology and urodynamics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 90
eISSN - 1520-6777
pISSN - 0733-2467
DOI - 10.1002/nau.22639
Subject(s) - medicine , electromyography , atrophy , diabetes mellitus , external anal sphincter , motor unit , sphincter , polyneuropathy , conus medullaris , urology , surgery , physical medicine and rehabilitation , anatomy , spinal cord , endocrinology , rectum , anal canal , psychiatry
Aims Abnormalities of external anal sphincter electromyography (EAS‐EMG) characterize multiple system atrophy (MSA) and focal cauda equina or conus medullaris lesions. This study is designed to determine whether and how diabetic polyneuropathy (DPN) affects EAS as compared to the abnormalities seen in MSA. Methods We conducted multi‐motor unit potential (MUP) analysis of EAS in 22 healthy controls, 32 diabetes mellitus (DM) patients without neuropathy, 38 DPN patients, and 68 MSA patients. Results DPN patients had a significant ( P < 0.01) increase in MUP mean duration, mean amplitude, percentage of long duration MUPs, and satellite rate, but to a lesser extent than MSA. Mean duration and satellite rate showed the least overlap among different groups in individual value distributions. Conclusions Compared with MSA, DPN affects EAS to a lesser degree as judged by neurogenic MUP abnormalities in EMG. Mean duration and satellite rate may serve as the most discriminating aspects in MUP analysis of EAS. Neurourol. Urodynam. 34:???–???, 2015 . © 2014 Wiley Periodicals, Inc.