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Scientific Programme, 42nd Annual Meeting of the International Continence Society (ICS) 15 – 19 October 2012, Beijing, China
Author(s) -
Gadjiev, N.,
Brovkin, S.,
Tabaza, Ruth,
Kirschner-Hermanns, Ruth
Publication year - 2012
Publication title -
neurourology and urodynamics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 90
eISSN - 1520-6777
pISSN - 0733-2467
DOI - 10.1002/nau.22287
Subject(s) - beijing , china , medicine , citation , library science , chinese society , political science , law , computer science
Hypothesis / aims of study ATP is released from the urothelium during bladder filling and its actions at purinergic receptors on bladder sensory nerves is an essential function of normal voiding behaviour, disruption of which leads to bladder hyporeflexia and disrupted micturition [1]. The TRPV1 receptor, also present on primary afferent fibres, is consistently implicated in inflammation and pain [2] and a more recent role in signalling during bladder filling has emerged [3]. The aim of this study was to determine the nature of interactions between TRPV1 and P2X receptors in modulating afferent nerve activity.