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Validation of the urinary sensation scale (USS)
Author(s) -
Coyne Karin S.,
Margolis Mary Kay,
Hsieh Ray,
Vats Vasudha,
Chapple Christopher R.
Publication year - 2011
Publication title -
neurourology and urodynamics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 90
eISSN - 1520-6777
pISSN - 0733-2467
DOI - 10.1002/nau.21005
Subject(s) - nocturia , overactive bladder , medicine , international prostate symptom score , urinary urgency , lower urinary tract symptoms , urination , tolterodine , urinary system , physical therapy , urology , gynecology , prostate , alternative medicine , pathology , cancer
Abstract Aim The purpose of this study was to assess the validity of the Urinary Sensation Scale (USS) in men with overactive bladder and voiding symptoms (OAB‐LUTS) and women with overactive bladder (OAB). Methods Data from two OAB clinical trials of tolterodine were used. The USS, a 5‐point scale, assesses the amount of urinary urgency associated with each urination. Three methods to calculate the USS are: mean urgency (Mean USS); mode urgency (Mode USS); and sum urgency (sum USS). The validity and responsiveness of the scoring methods was assessed using Spearman's correlations, general linear models, and effect sizes. Results Data from 650 men (Study 1) and 413 women (Study 2) were analyzed. Mean age was 65.2 (men) and 47.8 (women); 70% were Caucasian in both studies. Correlations of USS scores with bladder diary variables were small to moderate and higher among Sum USS than Mean USS (r = 0.02–0.64). Correlations among the USS and patient‐reported outcomes (PROs) were again small to moderate and higher with Sum USS (r = 0.05–0.41). Both the Mean USS and Sum USS significantly discriminated (all P < 0.001) among all bladder diary variables (except nocturia and UUI in men) when grouped as improved/not improved as well as by the PROs. Effect sizes for men and women, respectively, were −0.52 and −1.09 for Mean USS and −0.72 and −1.36 for Sum USS. Conclusion The USS is a valid and highly responsive measure of urinary urgency in men with OAB‐LUTS and women with OAB. Neurourol. Urodynam. 30:360–365, 2011. © 2011 Wiley‐Liss, Inc.