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Patient reported outcomes tools in an observational study of female stress urinary incontinence
Author(s) -
van de Vaart Huub,
Falconer Christian,
Quail Deborah,
Timlin Louise,
Manning Martina,
Tincello Douglas,
Tunn Ralf
Publication year - 2010
Publication title -
neurourology and urodynamics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 90
eISSN - 1520-6777
pISSN - 0733-2467
DOI - 10.1002/nau.20722
Subject(s) - medicine , urinary incontinence , quality of life (healthcare) , observational study , distress , stress incontinence , physical therapy , genitourinary system , urology , clinical psychology , nursing
Aims: To determine which patient characteristics, incontinence and non‐incontinence related, are associated with the symptom severity scores of the Urogenital Distress Inventory (UDI) and the International Consultation on Incontinence Questionnaire Urinary Incontinence (ICIQ‐UI); and to determine the association of both patient characteristics and symptom severity scores with quality‐of‐life scores of the Incontinence Impact Questionnaire (IIQ) and the Incontinence‐Quality of Life (I‐QOL) questionnaire. Methods: Women presenting with stress urinary incontinence (SUI) symptoms in primary and secondary care entered the Stress Urinary Incontinence Treatment Study (SUIT), an observational study evaluating the cost‐effectiveness of duloxetine compared to other non‐surgical treatments for SUI. At enrolment patients completed the UDI‐6, the short form ICIQ‐UI, the IIQ‐7 and the I‐QOL. Multivariate linear regressions were performed with the UDI‐6, ICIQ‐UI SF, IIQ‐7, and I‐QOL as outcomes.Results: The total number of incontinence episodes is the most significant explanatory variable of the two symptom questionnaire scores, but the UDI‐6 score also reflects the type of incontinence. The variability of the condition‐specific quality‐of‐life questionnaires is primarily explained by the symptom severity questionnaire scores. Although there is a high intercorrelation, both these symptom questionnaires independently contributed significantly to the IIQ‐7 and I‐QOL total scores. Conclusions: The UDI‐6 and ICIQ‐UI SF can be regarded as scientifically sound symptom questionnaires in UI evaluation; but they have differences. Since the UDI‐6 and ICIQ‐UI SF independently contribute to the quality‐of‐life scores, this suggests that in incontinence research symptom questionnaires should not focus only on incontinence, but on a broader range of urogenital symptoms. Neurourol. Urodynam. 29:348–353, 2010. © 2009 Wiley‐Liss, Inc.