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Abnormal pedal thermoregulation in interstitial cystitis
Author(s) -
Irwin Paul P.,
James Susan,
Watts Lynda,
Fleming Lamar L.,
Galloway Niall T. M.
Publication year - 1993
Publication title -
neurourology and urodynamics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 90
eISSN - 1520-6777
pISSN - 0733-2467
DOI - 10.1002/nau.1930120207
Subject(s) - interstitial cystitis , medicine , vasomotor , thermoregulation , skin temperature , cold stress , volunteer , anesthesia , sympathetic activity , urinary system , heart rate , dermatology , biochemistry , chemistry , biology , agronomy , gene , blood pressure
Isolated cold stress tests were used to evaluate the thermoregulatory capacity in the feet of 19 patients with interstitial cystitis (IC) and of 11 healthy volunteer control subjects. Mean pedal skin temperature fell more rapidly in the IC group as compared with controls; significant differences were found at 10‐min ( P = 0.002) and 20‐min ( P = 0.0008) cooling. Mean skin temperature remained lower in the IC group throughout the study. Sixteen feet (42%) in the IC group and five (22%) of the control feet failed to return to within 2°C of baseline temperature during the 20‐min recovery period. These findings may reflect abnormal vasomotor control in the IC group and, if so, may be indicative of increased spinal sympathetic activity in interstitial cystitis.