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Bladder and urethral pressures during bladder filling in patients with multiple sclerosis and urge incontinence
Author(s) -
Kinn AnneCharlotte,
Nergårdh Arne,
Sidén ÅKe
Publication year - 1985
Publication title -
neurourology and urodynamics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 90
eISSN - 1520-6777
pISSN - 0733-2467
DOI - 10.1002/nau.1930040206
Subject(s) - medicine , hyperreflexia , atropine , urology , urge incontinence , multiple sclerosis , urinary incontinence , detrusor instability , urination , anesthesia , urinary system , psychiatry
Abstract Twenty patients with multiple sclerosis and distressing urge incontinence underwent continuous measuring of bladder and urethral pressures during bladder filling. Hyperreflexia with high‐pressure peaks resulted in more excessive leakage than detrusor instability with frequent recurring pressure rises of low amplitude and short duration. Atropine reduced leakage by decrease of amplitude as well as frequency of the detrusor contractions. In some patients atropine also normalized urethral instability. Thus it seems probable that both hyperreflexia and instability in patients with multiple sclerosis are mediated by cholinergic neurones in the bladder wall.