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The development of reflex bladder activity following spinal cord injury in cats and a method to control it
Author(s) -
McGuire Edward J.,
Morrissey Susan G.
Publication year - 1982
Publication title -
neurourology and urodynamics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 90
eISSN - 1520-6777
pISSN - 0733-2467
DOI - 10.1002/nau.1930010214
Subject(s) - dyssynergia , medicine , spinal cord injury , spinal cord , reflex , cats , anesthesia , urinary bladder , detrusor sphincter dyssynergia , inhibitory postsynaptic potential , sphincter , anal sphincter , urinary system , stimulation , urology , anatomy , surgery , psychiatry
Spinal cord transection is associated with the development of detrusor external sphincter dyssynergia in cats. These findings indicate that the cat is a suitable model for the study of lower urinary tract dysfunction after spinal cord injury. Inhibition of reflex detrusor activity was achieved by activation of a sacral inhibitory pathway by electrical stimulation of the sacral roots or anal sphincter in normal and spinal—injured animals, indicating presence of a sacral inhibitory pathway.