Open AccessApplications of metal–organic frameworks for oral delivery systems
Author(s) -
Jiao Wenjuan,
Chi Chengdeng
Publication year - 2022
Publication title -
nano select
Language(s) - English
Resource type - Journals
ISSN - 2688-4011
DOI - 10.1002/nano.202100258
Subject(s) - metal organic framework , nanotechnology , dilemma , destiny (iss module) , delivery system , risk analysis (engineering) , computer science , medicine , materials science , engineering , chemistry , biomedical engineering , philosophy , organic chemistry , epistemology , adsorption , aerospace engineering
Abstract Metal–organic frameworks (MOFs) have been developed to be intelligent delivery systems recently. However, MOFs as oral systems have been challenging. The purpose of this perspective is to briefly review the current applications of oral MOFs and the present dilemma of oral MOFs for humans. The destiny of MOFs‐based materials within the gastrointestinal tract and the blood are discussed, and the principles that guide the development of oral MOFs‐based materials are summarized. It is expected that this perspective will provide new insights on the design and development of oral MOF‐based materials as smart carriers for keeping human health.