Open AccessConfined interface vibration for femtoliter droplets generation and manipulation
Author(s) -
Li Dege,
Huang Bingfang,
Cao Yi,
Han Molong,
Wu Xinlei,
Sun Qiang,
Ma Chi,
Zhao Lilong,
Liu Peng,
Zheng Chao,
Dong Hang,
Wang Xiaolong,
Liu Yonghong,
Zhang Yanzhen
Publication year - 2021
Publication title -
nano select
Language(s) - English
Resource type - Journals
ISSN - 2688-4011
DOI - 10.1002/nano.202000151
Subject(s) - microfluidics , nozzle , nanotechnology , pipette , interface (matter) , vibration , materials science , computer science , chemistry , mechanical engineering , acoustics , physics , engineering , capillary action , capillary number , composite material
The precise and effective generation and manipulation of micron‐sized droplets is crucial for chemical and biological research and applications. Normally, droplets generation and manipulation are achieved by two separate devices/systems with their respective operation strategies. Pipette, inkjet nozzle, and microfluidic channels equipped with programed syringes are commonly used for droplets generation whereas the subsequent manipulation is normally achieved by leveraging of forces originating either from optical, electric, magnetic or acoustic field and the corresponding complicated devices. Here we report a new paradigm that can realize simultaneous droplets generation and manipulation in an immiscible liquid environment using only the confined interface vibration generated by the ordinary inkjet nozzle. Droplets, ranging from femtoliter to picoliter, can be generated and manipulated without interruption since they are actuated by the same nozzle. Our strategy provides a platform for precise generation and manipulating the micro‐sized droplets that may be valuable for applications requiring simple setups and seamless connection between droplets generation and droplets manipulation.