Open AccessFundamentals and applications of nanoparticles for ultrasound‐based imaging and therapy
Author(s) -
Li Lujing,
Guan Yupeng,
Xiong Haiyun,
Deng Tian,
Ji Qiao,
Xu Zuofeng,
Kang Yang,
Pang Jun
Publication year - 2020
Publication title -
nano select
Language(s) - English
Resource type - Journals
ISSN - 2688-4011
DOI - 10.1002/nano.202000035
Subject(s) - sonodynamic therapy , modality (human–computer interaction) , nanotechnology , biomedicine , biosafety , cancer therapy , modalities , medical imaging , cancer imaging , medicine , medical physics , ultrasound , computer science , materials science , cancer , artificial intelligence , radiology , bioinformatics , pathology , social science , sociology , biology
Ultrasonography (US) is frequently applied in clinical imaging because of its inherent merits compared with those of other imaging methods. Nanoparticle (NP)‐based imaging and therapeutic modalities have been widely used because of their unique functionalities and high performance. The report is mainly about the classifications and applications of NPs for US‐based theranostic biomedicine. The US‐based applications include single‐modality US imaging, multimodality US imaging, high‐intensity focused US, US‐triggered drug release, US‐enhanced gene transfection, and US‐irradiated sonodynamic therapy. In addition, current challenges, including the biological effects and biosafety, are discussed in this interview. NPs have tremendous potential as a US‐based theranostic tool and have revealed a new direction in cancer therapy.