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Single fiber electromyography of extraocular muscles: A sensitive method for the diagnosis of ocular myasthenia gravis
Author(s) -
Rivero Alberto,
Crovetto Luis,
Lopez Lidia,
Maselli Ricardo,
Nogués Martín
Publication year - 1995
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.880180904
Subject(s) - medicine , electromyography , myasthenia gravis , extraocular muscles , ocular myasthenia , orbicularis oculi muscle , surgery , ophthalmology , eyelid , physical medicine and rehabilitation
We performed single fiber electromyography (SFEMG) in the superior rectus and levator palpebralis (SR‐LP) muscles of 17 patients with pure ocular myasthenia gravis (MG) and 9 controls. Thirteen patients were also assessed with SFEMG in the orbicularis oculi (OO) muscle. All the MG patients but none of the control subjects showed abnormal SFEMG jitter in the SR‐LP muscles. On the other hand, only 62% of the MG patients had abnormal SFEMG jitter in the OO muscle. The procedure was well tolerated by the patients, and complications were minor. We conclude that SFEMG of the SR–LP muscles is a safe and highly sensitive technique for the diagnosis of ocular MG. © 1995 John Wiley & Sons, Inc.