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Peripheral and central conduction in n ‐hexane polyneuropathya
Author(s) -
Öge A. Emre,
Yazici Jale,
Boyaciyan Arl,
Eryildiz Derya,
Örnek Ibrahim,
Konyaliǧlu Rana,
Cengiz Salih,
Okşak O. Zeki,
Asar Saim,
Baslo Aynur
Publication year - 1994
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.880171211
Subject(s) - stimulation , electromyography , polyneuropathy , motor nerve , transcranial magnetic stimulation , anatomy , median nerve , nerve conduction velocity , forearm , nerve conduction , peripheral , electrophysiology , medicine , physical medicine and rehabilitation
Electrophysiological findings of 27 males with industrial n ‐hexane polyneuropathy (HPNP) are presented. The results of needle electromyography and nerve conduction studies were compatible with primarily axonal polyneuropathy with secondary segmental demyelination. Motor conduction velocities were the slowest in distal regions of the nerves. In the proximal nerve segments, which were partly tested by magnetic stimulation of the nerve roots, this slowing was much less pronounced. The reduction in mean motor conduction velocities in the forearm segments of ulnar nerves was more than 30% in comparison to the control group means. This reduction was only 10% in the neckaxilla segments. We think that this finding is a reflection of the distal axonopathy process. Central motor conduction times calculated by transcranial magnetic stimulation and spinal nerve root stimulation were found to be prolonged in HPNP patients, indicating that descending motor pathways are affected in human HPNP. © 1994 John Wiley & Sons, Inc.