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Tuberculous infection of skeletal muscle in a case of dermatomyositis
Author(s) -
Davidson George S.,
Voorneveld Colin R.,
Krishnan Nirmala
Publication year - 1994
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.880170705
Subject(s) - dermatomyositis , medicine , skeletal muscle , immunosuppression , tuberculosis , autopsy , pathology , mycobacterium tuberculosis , immunology
A patient with dermatomyositis associated with carcinoma was treated with steroids and antibiotics for possible tuberculosis. Autopsy showed an overwhelming diffuse nongranulomatous infection of Mycobacterium tuberculosis involving only the skeletal muscles and one inguinal lymph node. The rare localization of tuberculosis to skeletal muscle in this case is possibly due to steroid immunosuppression and the humoral immune attack on muscle blood vessels that is a part of dermatomyositis. © 1994 John Wiley & Sons, Inc.