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Paraneoplastic pseudo‐obstruction, mononeuropathy multiplex, and sensory neuronopathy
Author(s) -
Liang Bertrand C.,
Albers James W.,
Sima Anders A. F.,
Nostrant Timothy T.
Publication year - 1994
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.880170113
Subject(s) - mononeuropathy , medicine , multiplex , sensory system , pathology , dermatology , peripheral neuropathy , neuroscience , bioinformatics , biology , endocrinology , diabetes mellitus
A patient with mononeuropathy multiplex, sensory neuronopathy, and diffuse intestinal pseudo‐obstruction consisting of gastroparesis and impaired small and large bowel motility was found to have a small cell carcinoma of the lung. The constellation of findings were indicative of paraneoplastic neuropathy, which was confirmed with the appropriate antibody studies demonstrating antineuronal nuclear antibodies. Identification of paraneoplastic neuropathy is important, since early treatment of the primary cancer, which is virtually always a small cell carcinoma of the lung, may halt the progression of the disorder. © 1994 John Wiley & Sons, Inc.