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Somatosensory evoked potentials induced by stimulating a variable number of nerve fibers in rat
Author(s) -
Zhao Shurun,
Kim Daniel H.,
Kline David G.,
Beuerman Roger W.,
Thompson Hilary W.
Publication year - 1993
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.880161112
Subject(s) - sural nerve , somatosensory evoked potential , somatosensory system , anatomy , lesion , spinal cord , medicine , stimulus (psychology) , stimulation , central nervous system , electrophysiology , anesthesia , neuroscience , chemistry , biology , pathology , psychology , psychotherapist
Abstract Somatosensory evoked potentials (SEPs) were recorded from rat spinal cord (sSEPs) and cerebral cortex (cSEPs). Stimulus sites included either one or both sural nerve branches having different fiber populations (group A), or distal to a lesion of controlled size of the sural nerve made 1 week earlier (group B). In the two groups of animals, amplitudes of SEPs correlated with the quantity of large myelinated nerve fibers. Peak latencies of sSEPs in group A related to the ratio of sizes of transmitting fibers. sSEPs and cSEPs in both groups A and B could be recorded in a reproducible fashion by stimulating sural nerve branches or lesioned nerve trunks containing only 100 or less nerve fibers greater than 4 m̈m in size. Thus, presence of sSEPs or cSEPs after stimulation distal to a lesion site does not insure that many nerve fibers have continuity with the central nervous system (CNS). © 1993 John Wiley & Sons, Inc.