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Sarcoid myopathy presenting with diaphragm weakness
Author(s) -
Dewberry Robert G.,
Phillips Lawrence H.,
Schneider Bernard F.,
Cale William F.
Publication year - 1993
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.880160805
Subject(s) - myopathy , weakness , medicine , diaphragm (acoustics) , muscle weakness , physical medicine and rehabilitation , pathology , anatomy , physics , acoustics , loudspeaker
Sarcoidosis involving muscle occurs frequently, but it is infrequently symptomatic. The clinical, electromyographic, and histologic features of sarcoidosis involving muscle in a 63‐year‐old woman presenting with diaphragm weakness are described. An electromyogram revealed widespread myotonia and an inflammatory myopathic process, suggestive of adult‐onset acid maltase deficiency disease. Muscle biopsy showed noncaseating granulomas consistent with sarcoidosis. Clinical improvement followed the initiation of oral prednisone therapy. This case illustrates that muscular sarcoidosis may mimic adult‐onset acid maltase deficiency in both its clinical and electromyographic features. © 1993 John Wiley & Sons, Inc.