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Invited review: Autonomic dysfunction in peripheral nerve disease
Author(s) -
McLeod James G.
Publication year - 1992
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.880150103
Subject(s) - dysautonomia , autonomic nervous system , medicine , peripheral , peripheral nervous system , peripheral neuropathy , sympathetic nervous system , pathological , amyloidosis , neuroscience , disease , diabetes mellitus , central nervous system , endocrinology , psychology , heart rate , blood pressure
The autonomic nervous system is affected, in most peripheral neuropathies. but only in a small number of conditions, such as diabetes, amyloidosis, Guillain‐Barré syndrome, porphyria, and familiar dysautonomia, is autonomic dysfunction of clinical importance. The pathological changes in the peripheral autonomic nervous system are similar to those in the peripheral somatic nerves. Autonomic disturbances are most likely to occur when there is acute demyelination or damage to small myelinated and unmyelinated fibers. Autonomic investigations should include tests of both sympathetic and parasympathetic function. Treatment consists of management of the underlying cause of peripheral neuropathy, physical and pharmacological measures.