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Chronic multifocal demyelinating neuropathy associated with central nervous system demyelination
Author(s) -
Naganuma Mutsuo,
Shima Kohji,
Matsumoto Akihisa,
Tashiro Kunio
Publication year - 1991
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.880141005
Subject(s) - medicine , central nervous system , demyelinating disease , optic neuritis , myelitis , neuritis , peripheral nervous system , multiple sclerosis , peripheral neuropathy , multifocal motor neuropathy , peripheral , central nervous system disease , pathology , spinal cord , mismatch negativity , immunology , surgery , electroencephalography , psychiatry , diabetes mellitus , endocrinology
We have carried out a long‐term study of lesions found in a man who had a demyelinating disease of both central and peripheral nervous systems. During the 10 years of his clinical course, he suffered from optic neuritis, multifocal myelitis, and chronic multifocal demyelinating neuropathy, with persistent conduction block. Our study revealed that both central and peripheral nervous system demyelination occurred repeatedly and simultaneously.