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Real‐time sonography of acute and chronic muscle denervation
Author(s) -
Gunreben Gerd,
Bogdahn Ulrich
Publication year - 1991
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.880140709
Subject(s) - denervation , medicine , ultrasound , pathological , lesion , electromyography , lower motor neuron , radiology , pathology , anatomy , motor neuron , disease , physical medicine and rehabilitation
Presented are real‐time ultrasound findings in partially and completely denervated muscles of 30 patients with focal neurpathy and various other disorders of the second motor neuron. Sonographic scans of affected muscles are analyzed in conjunction with unaffected muscles of the same individual, under identical examination conditions. Initial pathological ultrasound changes could be detected as soon as 2 weeks after an acute neurogenic lesion. In denervation, the echodensity of the muscle was high and the normal intramuscular pattern was decomposed. Findings were more intense in severe and longstanding denervation. Ultrasoudn‐indicated pathology correlated highly (chi‐square: P < 0.001) with pathological sponteneous activity detected by electromyography. Focal and systemic neuropathies showed no differences in ultrasound pathology. Six cases with central motor palsy had normal sonograms. Poor spatial resolution of real‐time ultrasonography–as compared with CT and MRI–is compensated by its bedside availability, frequent repeatability without patient risk and discomfort, and its in vivo correlation of muscle morphology with muscle function.