Premium
Hypertrophic mononeuritis clinically presenting with painful legs and moving toes
Author(s) -
Mitsumoto Hiroshi,
Levin Kerry H.,
Wilbourn Asa J.,
Chou Samuel M.
Publication year - 1990
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.880130308
Subject(s) - mononeuropathy , medicine , myokymia , lesion , anatomy , tibial nerve , electromyography , pathology , peripheral neuropathy , endocrinology , psychiatry , stimulation , diabetes mellitus
A 40‐year‐old woman presented with progressive lower leg pain and spontaneous toe movement. The EMG showed a posterior tibial nerve mononeuropathy and continuous myokymic discharges in posterior tibial‐innervated muscles. The MRI revealed a markedly enlarged posterior tibial nerve. Toe movements and myokymia were unaffected by the proximal transection of the lesion but ceased abruptly when the distal end of the fusiform “tumor” was resected, suggesting that spontaneous electrical foci may have been located along the nerve lesion. The markedly enlarged nerve segment contained edematous, swollen fascicles with marked Schwann cell onion‐bulb lesions and angiocentric, lymphocytic, and lymphofollicular infiltration. This nerve lesion is an example of a newly recognized entity called hypertrophic mononeuritis.