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Polyneuropathy in lithium intoxication
Author(s) -
Vanhooren Geert,
Dehaene Ides,
Van Zandycke Michel,
Piessens Frans,
Vandenbergh Vic,
Van Hees Johan,
Lammens Martin,
Carton Herwig
Publication year - 1990
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.880130306
Subject(s) - polyneuropathy , medicine , discontinuation , sural nerve , lithium (medication) , electromyography , lithium carbonate , anesthesia , nerve conduction , physical medicine and rehabilitation , surgery , chemistry , ion , organic chemistry , ionic bonding
Two patients developed acute sensorimotor polyneuropathy after intoxication with lithium carbonate. Nerve conduction studies, electromyography, and sural nerve biopsy proved it to be an axonal neuropathy. Recovery of muscle strength, reflexes, and sensory function started weeks after discontinuation of lithium therapy. One patient fully recovered within a year. In the literature we found nine other cases of lithium polyneuropathy.