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Electrodiagnostic evolution of carcinomatous sensory neuronopathy
Author(s) -
Donofrio Peter D.,
Alessi Anthony G.,
Albers James W.,
Knapp Robert H.,
Blaivas Mila
Publication year - 1989
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.880120612
Subject(s) - sensory system , sensory nerve , medicine , axon , electrophysiology , nerve root , motor function , neuroscience , peripheral , pathology , anatomy , biology , physical medicine and rehabilitation
Sensory neuronopathy is a well‐recognized remote effect of carcinoma. We report the clinical and electrodiagnostic evolution of a sensory neuronopathy in a patient with carcinoma of the lung. Serial electrophysiologic studies suggest transformation from normal peripheral nerve function through early posterior root involvement to absent sensory nerve function. Diffuse motor conduction abnormalities occurred late in the disease, perhaps reflecting motor axon changes associated with disuse.