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Muscle function in patients with primary hyperparathyroidism
Author(s) -
Joborn Charlotte,
Rastad Jonas,
Stålberg Erik,
Åkerström Göran,
Ljunghall Sverker
Publication year - 1989
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.880120202
Subject(s) - stimulation , medicine , muscle contraction , contraction (grammar) , primary hyperparathyroidism , skeletal muscle , adductor pollicis muscle , isometric exercise , muscle weakness , muscle fatigue , weakness , muscle relaxation , endocrinology , electromyography , anatomy , physical medicine and rehabilitation , ulnar nerve , elbow
The muscle contraction of the anterior tibial muscle was investigated by measurements of electrically stimulated and computer‐analyzed muscle twitches in 18 unselected patients with primary hyperparathyroidism (HPT) and in 20 healthy control persons. The HPT patients had a lower muscle twitch tension (TT) at single stimulation, compared with the control group [76 ± 24 N (SD) and 99 ± 33 N respectively, P < 0.05]. At high‐frequency stimulation the difference in muscle force increased, and at 20 Hz stimulation the force in the HPT patients was 73% of that in the controls ( P < 0.01). There were no differences between the HPT patients and the control persons in neither contraction time nor half relaxation time at single muscle twitch nor in twitch potentiation after 20 and 90 seconds maximal voluntary contraction. The results indicate that patients with primary HPT have an impaired muscle function of probable importance for their symptoms of weakness and generalized fatigue.