Premium
Ionic channels: II. Voltage‐ and agonist‐gated and agonist‐modified channel properties and structure
Author(s) -
Ruff Robert L.
Publication year - 1986
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.880090902
Subject(s) - agonist , sodium channel , chemistry , ion channel , biophysics , voltage gated ion channel , acetylcholine receptor , receptor , biochemistry , biology , sodium , organic chemistry
This article reviews the different forms of ionic channels: voltage‐gated, agonist‐gated, and agonist‐ and second messenger‐modified channels. The recent advances in our knowledge of the amino acid sequence of the sodium channel and the nicotinic acetylcholine receptor and the relationship of the primary structure to the channels' quarternary structure and function are discussed.