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Ionic channels: I. The biophysical basis for ion passage and channel gating
Author(s) -
Ruff Robert L.
Publication year - 1986
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.880090803
Subject(s) - gating , ion channel , sodium channel , ionic bonding , biophysics , conductance , chemistry , ion , membrane potential , voltage gated ion channel , electrophysiology , channel (broadcasting) , patch clamp , sodium , neuroscience , biochemistry , biology , computer science , physics , telecommunications , receptor , organic chemistry , condensed matter physics
This article reviews the biophysics of ion passage through membrane pores, as well as the physical factors that control the ion selectivity, gating, and conductance of an ionic channel. Different voltage clamp techniques are discussed in detail. The biophysical properties of sodium channels are reviewed.